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AOS5 FISH Probe

The AOS5 FISH probe is designed to hybridize to the AOS5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NOTCH1-20-OR  (Standard Design) 20 (40 μL) 200 μL
NOTCH1-20-RE 20 (40 μL) 200 μL
NOTCH1-20-GO 20 (40 μL) 200 μL
NOTCH1-20-GR 20 (40 μL) 200 μL
NOTCH1-20-AQ 20 (40 μL) 200 μL
NOTCH1-20-DIG 20 (40 μL) 200 μL
NOTCH1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]

Gene Details

Gene Symbol: NOTCH1

Gene Name: Notch 1

Chromosome: CHR9: 139388895-139440238

Locus: 9q34.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: AOS5 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NOTCH1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping