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APE2 FISH Probe

The APE2 FISH probe is designed to hybridize to the APE2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
APEX2-20-OR  (Standard Design) 20 (40 μL) 200 μL
APEX2-20-RE 20 (40 μL) 200 μL
APEX2-20-GO 20 (40 μL) 200 μL
APEX2-20-GR 20 (40 μL) 200 μL
APEX2-20-AQ 20 (40 μL) 200 μL
APEX2-20-DIG 20 (40 μL) 200 μL
APEX2-20-BIO 20 (40 μL) 200 μL

Gene Summary

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

Gene Details

Gene Symbol: APEX2

Gene Name: Apurinic/apyrimidinic Endodeoxyribonuclease 2

Chromosome: CHRX: 55026779-55034212

Locus: Xp11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: APE2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: APEX2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping