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ARB FISH Probe

The ARB FISH probe is designed to hybridize to the ARB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BEST1-20-OR  (Standard Design) 20 (40 μL) 200 μL
BEST1-20-RE 20 (40 μL) 200 μL
BEST1-20-GO 20 (40 μL) 200 μL
BEST1-20-GR 20 (40 μL) 200 μL
BEST1-20-AQ 20 (40 μL) 200 μL
BEST1-20-DIG 20 (40 μL) 200 μL
BEST1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]

Gene Details

Gene Symbol: BEST1

Gene Name: Bestrophin 1

Chromosome: CHR11: 61717355-61731935

Locus: 11q12.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ARB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BEST1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping