ARCI3 FISH Probe
The ARCI3 FISH probe is designed to hybridize to the ARCI3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALOXE3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-RE | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-GO | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-GR | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-AQ | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-DIG | 20 (40 μL) | 200 μL |  |
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| ALOXE3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: ALOXE3
Gene Name: Arachidonate Lipoxygenase 3
Chromosome: CHR17: 7999217-8022234
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARCI3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ALOXE3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping