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ASAH3 FISH Probe

The ASAH3 FISH probe is designed to hybridize to the ASAH3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ACER1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ACER1-20-RE 20 (40 μL) 200 μL
ACER1-20-GO 20 (40 μL) 200 μL
ACER1-20-GR 20 (40 μL) 200 μL
ACER1-20-AQ 20 (40 μL) 200 μL
ACER1-20-DIG 20 (40 μL) 200 μL
ACER1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010]

Gene Details

Gene Symbol: ACER1

Gene Name: Alkaline Ceramidase 1

Chromosome: CHR19: 6306509-6333640

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ASAH3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACER1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping