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ATAG1874 FISH Probe

The ATAG1874 FISH probe is designed to hybridize to the ATAG1874 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
NCSTN-20-OR  (Standard Design) 20 (40 μL) 200 μL
NCSTN-20-RE 20 (40 μL) 200 μL
NCSTN-20-GO 20 (40 μL) 200 μL
NCSTN-20-GR 20 (40 μL) 200 μL
NCSTN-20-AQ 20 (40 μL) 200 μL
NCSTN-20-DIG 20 (40 μL) 200 μL
NCSTN-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014]

Gene Details

Gene Symbol: NCSTN

Gene Name: Nicastrin

Chromosome: CHR1: 160313062-160328742

Locus: 1q23.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ATAG1874 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: NCSTN-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping