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AV039194 FISH Probe

The AV039194 FISH probe is designed to hybridize to the AV039194 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SPAM1-20-OR  (Standard Design) 20 (40 μL) 200 μL
SPAM1-20-RE 20 (40 μL) 200 μL
SPAM1-20-GO 20 (40 μL) 200 μL
SPAM1-20-GR 20 (40 μL) 200 μL
SPAM1-20-AQ 20 (40 μL) 200 μL
SPAM1-20-DIG 20 (40 μL) 200 μL
SPAM1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Hyaluronidase degrades hyaluronic acid, a major structural proteoglycan found in extracellular matrices and basement membranes. Six members of the hyaluronidase family are clustered into two tightly linked groups on chromosome 3p21.3 and 7q31.3. This gene was previously referred to as HYAL1 and HYA1 and has since been assigned the official symbol SPAM1; another family member on chromosome 3p21.3 has been assigned HYAL1. This gene encodes a GPI-anchored enzyme located on the human sperm surface and inner acrosomal membrane. This multifunctional protein is a hyaluronidase that enables sperm to penetrate through the hyaluronic acid-rich cumulus cell layer surrounding the oocyte, a receptor that plays a role in hyaluronic acid induced cell signaling, and a receptor that is involved in sperm-zona pellucida adhesion. Abnormal expression of this gene in tumors has implicated this protein in degradation of basement membranes leading to tumor invasion and metastasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Gene Details

Gene Symbol: SPAM1

Gene Name: Sperm Adhesion Molecule 1

Chromosome: CHR7: 123565285-123611461

Locus: 7q31.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: AV039194 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SPAM1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping