BAP1 FISH Probe
The BAP1 FISH probe is designed to hybridize to the BAP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BAP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BAP1-20-RE | 20 (40 μL) | 200 μL |  |
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| BAP1-20-GO | 20 (40 μL) | 200 μL |  |
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| BAP1-20-GR | 20 (40 μL) | 200 μL |  |
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| BAP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BAP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BAP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: BAP1
Gene Name: BRCA1 Associated Protein 1
Chromosome: CHR3: 52435024-52444009
Locus: 3p21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BAP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BAP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping