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BETA-TRCP FISH Probe

The BETA-TRCP FISH probe is designed to hybridize to the BETA-TRCP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BTRC-20-OR  (Standard Design) 20 (40 μL) 200 μL
BTRC-20-RE 20 (40 μL) 200 μL
BTRC-20-GO 20 (40 μL) 200 μL
BTRC-20-GR 20 (40 μL) 200 μL
BTRC-20-AQ 20 (40 μL) 200 μL
BTRC-20-DIG 20 (40 μL) 200 μL
BTRC-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6. [provided by RefSeq, Mar 2012]

Gene Details

Gene Symbol: BTRC

Gene Name: Beta-transducin Repeat Containing E3 Ubiquitin Protein Ligase

Chromosome: CHR10: 103113824-103317070

Locus: 10q24.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: BETA-TRCP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BTRC-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping