C-FMS FISH Probe
The C-FMS FISH probe is designed to hybridize to the C-FMS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CSF1R-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-RE | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-GO | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-GR | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-AQ | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-DIG | 20 (40 μL) | 200 μL |  |
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| CSF1R-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: CSF1R
Gene Name: Colony Stimulating Factor 1 Receptor
Chromosome: CHR5: 149432853-149492935
Locus: 5q32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C-FMS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CSF1R-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping