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CD135 FISH Probe

The CD135 FISH probe is designed to hybridize to the CD135 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FLT3-20-OR  (Standard Design) 20 (40 μL) 200 μL
FLT3-20-RE 20 (40 μL) 200 μL
FLT3-20-GO 20 (40 μL) 200 μL
FLT3-20-GR 20 (40 μL) 200 μL
FLT3-20-AQ 20 (40 μL) 200 μL
FLT3-20-DIG 20 (40 μL) 200 μL
FLT3-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

Gene Details

Gene Symbol: FLT3

Gene Name: Fms Related Tyrosine Kinase 3

Chromosome: CHR13: 28577410-28674729

Locus: 13q12.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CD135 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FLT3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping