CDH10 FISH Probe
The CDH10 FISH probe is designed to hybridize to the CDH10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDH10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDH10-20-RE | 20 (40 μL) | 200 μL |  |
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| CDH10-20-GO | 20 (40 μL) | 200 μL |  |
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| CDH10-20-GR | 20 (40 μL) | 200 μL |  |
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| CDH10-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDH10-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDH10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CDH10
Gene Name: Cadherin 10
Chromosome: CHR5: 24487208-24645085
Locus: 5p14.2-p14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDH10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDH10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping