CEP104 FISH Probe
The CEP104 FISH probe is designed to hybridize to the CEP104 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CEP104-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-RE | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-GO | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-GR | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CEP104-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity. The mammalian protein contains three amino-terminal hydrophobic domains, two glycosylation sites, four cysteine-rich motifs, and two regions with homology to the glutamate receptor ionotropic, NMDA 1 protein. During ciliogenesis, the encoded protein translocates from the distal tips of the centrioles to the tip of the elongating cilium. Knockdown of the protein in human retinal pigment cells results in severe defects in ciliogenesis with structural deformities at the ciliary tips. Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome, which is characterized by a distinctive mid-hindbrain and cerebellar malformation, oculomotor apraxia, irregular breathing, developmental delay, and ataxia. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: CEP104
Gene Name: Centrosomal Protein 104
Chromosome: CHR1: 3728644-3773797
Locus: 1p36.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CEP104 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CEP104-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping