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CG18285-PA FISH Probe

The CG18285-PA FISH probe is designed to hybridize to the CG18285-PA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IGL-20-OR  (Standard Design) 20 (40 μL) 200 μL
IGL-20-RE 20 (40 μL) 200 μL
IGL-20-GO 20 (40 μL) 200 μL
IGL-20-GR 20 (40 μL) 200 μL
IGL-20-AQ 20 (40 μL) 200 μL
IGL-20-DIG 20 (40 μL) 200 μL
IGL-20-BIO 20 (40 μL) 200 μL

Gene Summary

Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: IGL

Gene Name: Immunoglobulin Lambda Locus

Chromosome: CHR22: 22026075-22922912

Locus: 22q11.22

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CG18285-PA FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: IGL-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping