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CG4145-PB FISH Probe

The CG4145-PB FISH probe is designed to hybridize to the CG4145-PB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
COL4A1-20-OR  (Standard Design) 20 (40 μL) 200 μL
COL4A1-20-RE 20 (40 μL) 200 μL
COL4A1-20-GO 20 (40 μL) 200 μL
COL4A1-20-GR 20 (40 μL) 200 μL
COL4A1-20-AQ 20 (40 μL) 200 μL
COL4A1-20-DIG 20 (40 μL) 200 μL
COL4A1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Gene Details

Gene Symbol: COL4A1

Gene Name: Collagen Type IV Alpha 1 Chain

Chromosome: CHR13: 110801309-110959496

Locus: 13q34

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CG4145-PB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: COL4A1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping