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CG6496-PA FISH Probe

The CG6496-PA FISH probe is designed to hybridize to the CG6496-PA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PDF-20-OR  (Standard Design) 20 (40 μL) 200 μL
PDF-20-RE 20 (40 μL) 200 μL
PDF-20-GO 20 (40 μL) 200 μL
PDF-20-GR 20 (40 μL) 200 μL
PDF-20-AQ 20 (40 μL) 200 μL
PDF-20-DIG 20 (40 μL) 200 μL
PDF-20-BIO 20 (40 μL) 200 μL

Gene Summary

Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq, Nov 2008]

Gene Details

Gene Symbol: PDF

Gene Name: Peptide Deformylase, Mitochondrial

Chromosome: CHR16: 69362523-69364498

Locus: 16q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CG6496-PA FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PDF-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping