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CRS FISH Probe

The CRS FISH probe is designed to hybridize to the CRS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TWIST1-20-OR  (Standard Design) 20 (40 μL) 200 μL
TWIST1-20-RE 20 (40 μL) 200 μL
TWIST1-20-GO 20 (40 μL) 200 μL
TWIST1-20-GR 20 (40 μL) 200 μL
TWIST1-20-AQ 20 (40 μL) 200 μL
TWIST1-20-DIG 20 (40 μL) 200 μL
TWIST1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: TWIST1

Gene Name: Twist Family BHLH Transcription Factor 1

Chromosome: CHR7: 19155090-19157295

Locus: 7p21.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CRS FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TWIST1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping