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CYBB FISH Probe

The CYBB FISH probe is designed to hybridize to the CYBB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CYBB-20-OR  (Standard Design) 20 (40 μL) 200 μL
CYBB-20-RE 20 (40 μL) 200 μL
CYBB-20-GO 20 (40 μL) 200 μL
CYBB-20-GR 20 (40 μL) 200 μL
CYBB-20-AQ 20 (40 μL) 200 μL
CYBB-20-DIG 20 (40 μL) 200 μL
CYBB-20-BIO 20 (40 μL) 200 μL

Gene Summary

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CYBB

Gene Name: Cytochrome B-245 Beta Chain

Chromosome: CHRX: 37639269-37672714

Locus: Xp21.1-p11.4

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CYBB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CYBB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping