CYP3A7-CYP3A51P FISH Probe
The CYP3A7-CYP3A51P FISH probe is designed to hybridize to the CYP3A7-CYP3A51P gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP3A7-CYP3A51P-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP3A7-CYP3A51P-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This locus represents readthrough transcription between the neighboring CYP3A7 (cytochrome P450, family 3, subfamily A, polypeptide 7) and CYP3A51P (cytochrome P450, family 3, subfamily A, polypeptide 51, pseudogene) genes, which are members of the CYP3A gene cluster on chromosome 7. The downstream pseudogene is not known to be independently transcribed. The readthrough transcript includes CYP3A7 exons 1-13 and exons 2 and 13 of the pseudogene. It encodes a CYP3A isoform with a novel C-terminus. This isoform is only expressed in alleles containing a T nucleotide at the -6 position of a splice acceptor in the pseudogene, which enables correct splicing of the upstream CYP3A7 exons to the pseudogene exons. It should be noted that the reference genome sequence represents the CYP3A7_39256 T->A allele, and thus this haplotype is unlikely to produce the readthrough transcript. [provided by RefSeq, Jan 2015]
Gene Details
Gene Symbol: CYP3A7-CYP3A51P
Gene Name: CYP3A7-CYP3A51P Readthrough
Chromosome: CHR7: 99735199-99684678
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP3A7-CYP3A51P FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP3A7-CYP3A51P-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping