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CYPIIIA21 FISH Probe

The CYPIIIA21 FISH probe is designed to hybridize to the CYPIIIA21 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CYP3A4-20-OR  (Standard Design) 20 (40 μL) 200 μL
CYP3A4-20-RE 20 (40 μL) 200 μL
CYP3A4-20-GO 20 (40 μL) 200 μL
CYP3A4-20-GR 20 (40 μL) 200 μL
CYP3A4-20-AQ 20 (40 μL) 200 μL
CYP3A4-20-DIG 20 (40 μL) 200 μL
CYP3A4-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]

Gene Details

Gene Symbol: CYP3A4

Gene Name: Cytochrome P450 Family 3 Subfamily A Member 4

Chromosome: CHR7: 99354582-99381811

Locus: 7q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CYPIIIA21 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CYP3A4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping