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DD3 FISH Probe

The DD3 FISH probe is designed to hybridize to the DD3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PCA3-20-OR  (Standard Design) 20 (40 μL) 200 μL
PCA3-20-RE 20 (40 μL) 200 μL
PCA3-20-GO 20 (40 μL) 200 μL
PCA3-20-GR 20 (40 μL) 200 μL
PCA3-20-AQ 20 (40 μL) 200 μL
PCA3-20-DIG 20 (40 μL) 200 μL
PCA3-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene produces a spliced, long non-coding RNA that is highly overexpressed in most types of prostate cancer cells and is used as a specific biomarker for this type of cancer. This gene is embedded in an intronic region of the prune2 gene on the opposite DNA strand. The transcript regulates prune2 levels through formation of a double-stranded RNA that undergoes adenosine deaminase acting on RNA-dependent adenosine-to-inosine RNA editing. In prostate cancer derived cells, overexpression of PCA induced downregulation of prune2, leading to decreased cell proliferation. Conversely, silencing in prostate cancer cells resulted in increased proliferation. Regulation of this gene appears to be sensitive to androgen-receptor activation, a molecular signature of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]

Gene Details

Gene Symbol: PCA3

Gene Name: Prostate Cancer Associated 3 (non-protein Coding)

Chromosome: CHR9: 79379353-79402465

Locus: 9q21.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DD3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PCA3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping