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DER-1 FISH Probe

The DER-1 FISH probe is designed to hybridize to the DER-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DERL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
DERL1-20-RE 20 (40 μL) 200 μL
DERL1-20-GO 20 (40 μL) 200 μL
DERL1-20-GR 20 (40 μL) 200 μL
DERL1-20-AQ 20 (40 μL) 200 μL
DERL1-20-DIG 20 (40 μL) 200 μL
DERL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

Gene Details

Gene Symbol: DERL1

Gene Name: Derlin 1

Chromosome: CHR8: 124025567-124054648

Locus: 8q24.13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DER-1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DERL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping