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DFNA2A FISH Probe

The DFNA2A FISH probe is designed to hybridize to the DFNA2A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KCNQ4-20-OR  (Standard Design) 20 (40 μL) 200 μL
KCNQ4-20-RE 20 (40 μL) 200 μL
KCNQ4-20-GO 20 (40 μL) 200 μL
KCNQ4-20-GR 20 (40 μL) 200 μL
KCNQ4-20-AQ 20 (40 μL) 200 μL
KCNQ4-20-DIG 20 (40 μL) 200 μL
KCNQ4-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: KCNQ4

Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 4

Chromosome: CHR1: 41249683-41306124

Locus: 1p34.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DFNA2A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KCNQ4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping