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DKCB3 FISH Probe

The DKCB3 FISH probe is designed to hybridize to the DKCB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
WRAP53-20-OR  (Standard Design) 20 (40 μL) 200 μL
WRAP53-20-RE 20 (40 μL) 200 μL
WRAP53-20-GO 20 (40 μL) 200 μL
WRAP53-20-GR 20 (40 μL) 200 μL
WRAP53-20-AQ 20 (40 μL) 200 μL
WRAP53-20-DIG 20 (40 μL) 200 μL
WRAP53-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]

Gene Details

Gene Symbol: WRAP53

Gene Name: WD Repeat Containing Antisense To TP53

Chromosome: CHR17: 7589388-7606820

Locus: 17p13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DKCB3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: WRAP53-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping