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DL2 FISH Probe

The DL2 FISH probe is designed to hybridize to the DL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TNFSF10-20-OR  (Standard Design) 20 (40 μL) 200 μL
TNFSF10-20-RE 20 (40 μL) 200 μL
TNFSF10-20-GO 20 (40 μL) 200 μL
TNFSF10-20-GR 20 (40 μL) 200 μL
TNFSF10-20-AQ 20 (40 μL) 200 μL
TNFSF10-20-DIG 20 (40 μL) 200 μL
TNFSF10-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Gene Details

Gene Symbol: TNFSF10

Gene Name: TNF Superfamily Member 10

Chromosome: CHR3: 172223297-172241297

Locus: 3q26.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DL2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TNFSF10-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping