DUX4L FISH Probe
The DUX4L FISH probe is designed to hybridize to the DUX4L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DUX4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DUX4-20-RE | 20 (40 μL) | 200 μL |  |
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| DUX4-20-GO | 20 (40 μL) | 200 μL |  |
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| DUX4-20-GR | 20 (40 μL) | 200 μL |  |
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| DUX4-20-AQ | 20 (40 μL) | 200 μL |  |
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| DUX4-20-DIG | 20 (40 μL) | 200 μL |  |
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| DUX4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: DUX4
Gene Name: Double Homeobox 4
Chromosome: CHR10: 135483677-135488584
Locus: 4q35.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DUX4L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DUX4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping