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E6-AP FISH Probe

The E6-AP FISH probe is designed to hybridize to the E6-AP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UBE3A-20-OR  (Standard Design) 20 (40 μL) 200 μL
UBE3A-20-RE 20 (40 μL) 200 μL
UBE3A-20-GO 20 (40 μL) 200 μL
UBE3A-20-GR 20 (40 μL) 200 μL
UBE3A-20-AQ 20 (40 μL) 200 μL
UBE3A-20-DIG 20 (40 μL) 200 μL
UBE3A-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: UBE3A

Gene Name: Ubiquitin Protein Ligase E3A

Chromosome: CHR15: 25582395-25684175

Locus: 15q11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: E6-AP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: UBE3A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping