ECS4 FISH Probe
The ECS4 FISH probe is designed to hybridize to the ECS4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CNE9-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CNE9-20-RE | 20 (40 μL) | 200 μL |  |
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| CNE9-20-GO | 20 (40 μL) | 200 μL |  |
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| CNE9-20-GR | 20 (40 μL) | 200 μL |  |
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| CNE9-20-AQ | 20 (40 μL) | 200 μL |  |
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| CNE9-20-DIG | 20 (40 μL) | 200 μL |  |
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| CNE9-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This genomic element is found within the pseudoautosomal region 1 (PAR1) of chromosomes X and Y, where each chromosome contains the same DNA region. It is located approximately 215 kb downstream of the SHOX (short stature homeobox) gene, and is one of several conserved elements that surround that gene. It can function as an enhancer of SHOX gene expression. Chromosome conformation capture (3C) assays show that the orthologous chicken region can form looping interactions with a region upstream of the SHOX gene in chicken limb. Mutations that include this human element, including deletions and microduplications, are associated with Leri-Weill dyschondrosteosis (LWD) and idiopathic short stature (ISS), and they have also been implicated in autism spectrum disorders (ASDs) and related neurodevelopmental conditions. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: CNE9
Gene Name: CNE9 Enhancer Downstream Of SHOX
Locus: Xp22.33; Yp11.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ECS4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CNE9-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping