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EST1C FISH Probe

The EST1C FISH probe is designed to hybridize to the EST1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SMG7-20-OR  (Standard Design) 20 (40 μL) 200 μL
SMG7-20-RE 20 (40 μL) 200 μL
SMG7-20-GO 20 (40 μL) 200 μL
SMG7-20-GR 20 (40 μL) 200 μL
SMG7-20-AQ 20 (40 μL) 200 μL
SMG7-20-DIG 20 (40 μL) 200 μL
SMG7-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]

Gene Details

Gene Symbol: SMG7

Gene Name: SMG7, Nonsense Mediated MRNA Decay Factor

Chromosome: CHR1: 183441505-183523328

Locus: 1q25.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: EST1C FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SMG7-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping