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FEN1A FISH Probe

The FEN1A FISH probe is designed to hybridize to the FEN1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FEN1-20-OR  (Standard Design) 20 (40 μL) 200 μL
FEN1-20-RE 20 (40 μL) 200 μL
FEN1-20-GO 20 (40 μL) 200 μL
FEN1-20-GR 20 (40 μL) 200 μL
FEN1-20-AQ 20 (40 μL) 200 μL
FEN1-20-DIG 20 (40 μL) 200 μL
FEN1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: FEN1

Gene Name: Flap Structure-specific Endonuclease 1

Chromosome: CHR11: 61560108-61564714

Locus: 11q12.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: FEN1A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FEN1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping