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FHOD1-1 FISH Probe

The FHOD1-1 FISH probe is designed to hybridize to the FHOD1-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FHOD3-20-OR  (Standard Design) 20 (40 μL) 200 μL
FHOD3-20-RE 20 (40 μL) 200 μL
FHOD3-20-GO 20 (40 μL) 200 μL
FHOD3-20-GR 20 (40 μL) 200 μL
FHOD3-20-AQ 20 (40 μL) 200 μL
FHOD3-20-DIG 20 (40 μL) 200 μL
FHOD3-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the diaphanous-related formins (DRF), and contains multiple domains, including GBD (GTPase-binding domain), DID (diaphanous inhibitory domain), FH1 (formin homology 1), FH2 (formin homology 2), and DAD (diaphanous auto-regulatory domain) domains. This protein is thought to play a role in actin filament polymerization in cardiomyocytes. Mutations in this gene have been associated with dilated cardiomyopathy (DCM), characterized by dilation of the ventricular chamber, leading to impairment of systolic pump function and subsequent heart failure. Increased levels of the protein encoded by this gene have been observed in individuals with hypertrophic cardiomyopathy (HCM). Alternative splicing results in multiple transcript variants encoding different isoforms. A muscle-specific isoform has been shown to possess a casein kinase 2 (CK2) phosphorylation site at the C-terminal end of the FH2 domain. Phosphorylation of this site alters its interaction with sequestosome 1 (SQSTM1), and targets this isoform to myofibrils, while other isoforms form cytoplasmic aggregates. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol: FHOD3

Gene Name: Formin Homology 2 Domain Containing 3

Chromosome: CHR18: 33877701-34360018

Locus: 18q12.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: FHOD1-1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FHOD3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping