FHR-5 FISH Probe
The FHR-5 FISH probe is designed to hybridize to the FHR-5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CFHR5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-RE | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-GO | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-GR | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-AQ | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-DIG | 20 (40 μL) | 200 μL |  |
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| CFHR5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: CFHR5
Gene Name: Complement Factor H Related 5
Chromosome: CHR1: 196946666-196978803
Locus: 1q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FHR-5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CFHR5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping