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FSHD1A FISH Probe

The FSHD1A FISH probe is designed to hybridize to the FSHD1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FSHMD1A-20-OR  (Standard Design) 20 (40 μL) 200 μL
FSHMD1A-20-RE 20 (40 μL) 200 μL
FSHMD1A-20-GO 20 (40 μL) 200 μL
FSHMD1A-20-GR 20 (40 μL) 200 μL
FSHMD1A-20-AQ 20 (40 μL) 200 μL
FSHMD1A-20-DIG 20 (40 μL) 200 μL
FSHMD1A-20-BIO 20 (40 μL) 200 μL

Gene Summary

Facioscapulohumeral muscular dystrophy (FSHD) is a common hereditary disease of muscle. Patients with FSHD have a chromosomal rearrangement within the subtelomeric region of chromosome 4 (4q35). This region is composed mainly of a polymorphic repeat structure consisting of 3.3 kb repeat units, designated D4Z4. The number of repeat units varies from 10 to more than 100 in the population, however, in FSHD patients only 1-10 repeat units is observed because of a deletion of an integral number of these units. FSHD is caused by an epigenetic mechanism involving the contraction of a subtelomeric macrosatellite repeat, which results in marked hypomethylation of the contracted D4Z4 allele. It is likely not the structure, but the deregulation of transcription of one or more genes as a result of repeat-contraction-mediated chromatin alterations, that causes FSHD. [provided by RefSeq, Sep 2011]

Gene Details

Gene Symbol: FSHMD1A

Gene Name: Facioscapulohumeral Muscular Dystrophy 1A

Locus: 4q35

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: FSHD1A FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FSHMD1A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping