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GCK FISH Probe

The GCK FISH probe is designed to hybridize to the GCK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
GCK-20-OR  (Standard Design) 20 (40 μL) 200 μL
GCK-20-RE 20 (40 μL) 200 μL
GCK-20-GO 20 (40 μL) 200 μL
GCK-20-GR 20 (40 μL) 200 μL
GCK-20-AQ 20 (40 μL) 200 μL
GCK-20-DIG 20 (40 μL) 200 μL
GCK-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the hexokinase family of proteins. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver. In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen. Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: GCK

Gene Name: Glucokinase

Chromosome: CHR7: 44183869-44229022

Locus: 7p13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: GCK FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: GCK-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping