GRID2 FISH Probe
The GRID2 FISH probe is designed to hybridize to the GRID2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRID2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRID2-20-RE | 20 (40 μL) | 200 μL |  |
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| GRID2-20-GO | 20 (40 μL) | 200 μL |  |
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| GRID2-20-GR | 20 (40 μL) | 200 μL |  |
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| GRID2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRID2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRID2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: GRID2
Gene Name: Glutamate Ionotropic Receptor Delta Type Subunit 2
Chromosome: CHR4: 93225549-94693649
Locus: 4q22.1-q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: GRID2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRID2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping