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HMWK FISH Probe

The HMWK FISH probe is designed to hybridize to the HMWK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
KNG1-20-OR  (Standard Design) 20 (40 μL) 200 μL
KNG1-20-RE 20 (40 μL) 200 μL
KNG1-20-GO 20 (40 μL) 200 μL
KNG1-20-GR 20 (40 μL) 200 μL
KNG1-20-AQ 20 (40 μL) 200 μL
KNG1-20-DIG 20 (40 μL) 200 μL
KNG1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]

Gene Details

Gene Symbol: KNG1

Gene Name: Kininogen 1

Chromosome: CHR3: 186435097-186462199

Locus: 3q27.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HMWK FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KNG1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping