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HPLH2 FISH Probe

The HPLH2 FISH probe is designed to hybridize to the HPLH2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PRF1-20-OR  (Standard Design) 20 (40 μL) 200 μL
PRF1-20-RE 20 (40 μL) 200 μL
PRF1-20-GO 20 (40 μL) 200 μL
PRF1-20-GR 20 (40 μL) 200 μL
PRF1-20-AQ 20 (40 μL) 200 μL
PRF1-20-DIG 20 (40 μL) 200 μL
PRF1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: PRF1

Gene Name: Perforin 1

Chromosome: CHR10: 72357103-72362531

Locus: 10q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HPLH2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PRF1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping