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HUG-BR1 FISH Probe

The HUG-BR1 FISH probe is designed to hybridize to the HUG-BR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UGT1A1-20-OR  (Standard Design) 20 (40 μL) 200 μL
UGT1A1-20-RE 20 (40 μL) 200 μL
UGT1A1-20-GO 20 (40 μL) 200 μL
UGT1A1-20-GR 20 (40 μL) 200 μL
UGT1A1-20-AQ 20 (40 μL) 200 μL
UGT1A1-20-DIG 20 (40 μL) 200 μL
UGT1A1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: UGT1A1

Gene Name: UDP Glucuronosyltransferase Family 1 Member A1

Chromosome: CHR2: 234668918-234681945

Locus: 2q37.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HUG-BR1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: UGT1A1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping