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I7 FISH Probe

The I7 FISH probe is designed to hybridize to the I7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ACTN4-20-OR  (Standard Design) 20 (40 μL) 200 μL
ACTN4-20-RE 20 (40 μL) 200 μL
ACTN4-20-GO 20 (40 μL) 200 μL
ACTN4-20-GR 20 (40 μL) 200 μL
ACTN4-20-AQ 20 (40 μL) 200 μL
ACTN4-20-DIG 20 (40 μL) 200 μL
ACTN4-20-BIO 20 (40 μL) 200 μL

Gene Summary

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: ACTN4

Gene Name: Actinin Alpha 4

Chromosome: CHR19: 39138266-39221171

Locus: 19q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: I7 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ACTN4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping