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IL-12 FISH Probe

The IL-12 FISH probe is designed to hybridize to the IL-12 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IL12B-20-OR  (Standard Design) 20 (40 μL) 200 μL
IL12B-20-RE 20 (40 μL) 200 μL
IL12B-20-GO 20 (40 μL) 200 μL
IL12B-20-GR 20 (40 μL) 200 μL
IL12B-20-AQ 20 (40 μL) 200 μL
IL12B-20-DIG 20 (40 μL) 200 μL
IL12B-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: IL12B

Gene Name: Interleukin 12B

Chromosome: CHR5: 158741790-158757481

Locus: 5q33.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: IL-12 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: IL12B-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping