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INSDEGM FISH Probe

The INSDEGM FISH probe is designed to hybridize to the INSDEGM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
IDE-20-OR  (Standard Design) 20 (40 μL) 200 μL
IDE-20-RE 20 (40 μL) 200 μL
IDE-20-GO 20 (40 μL) 200 μL
IDE-20-GR 20 (40 μL) 200 μL
IDE-20-AQ 20 (40 μL) 200 μL
IDE-20-DIG 20 (40 μL) 200 μL
IDE-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009]

Gene Details

Gene Symbol: IDE

Gene Name: Insulin Degrading Enzyme

Chromosome: CHR10: 94211440-94333852

Locus: 10q23.33

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: INSDEGM FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: IDE-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping