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LYP FISH Probe

The LYP FISH probe is designed to hybridize to the LYP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SH2D1A-20-OR  (Standard Design) 20 (40 μL) 200 μL
SH2D1A-20-RE 20 (40 μL) 200 μL
SH2D1A-20-GO 20 (40 μL) 200 μL
SH2D1A-20-GR 20 (40 μL) 200 μL
SH2D1A-20-AQ 20 (40 μL) 200 μL
SH2D1A-20-DIG 20 (40 μL) 200 μL
SH2D1A-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: SH2D1A

Gene Name: SH2 Domain Containing 1A

Chromosome: CHRX: 123480131-123507010

Locus: Xq25

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: LYP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SH2D1A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping