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ME20-M FISH Probe

The ME20-M FISH probe is designed to hybridize to the ME20-M gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PMEL-20-OR  (Standard Design) 20 (40 μL) 200 μL
PMEL-20-RE 20 (40 μL) 200 μL
PMEL-20-GO 20 (40 μL) 200 μL
PMEL-20-GR 20 (40 μL) 200 μL
PMEL-20-AQ 20 (40 μL) 200 μL
PMEL-20-DIG 20 (40 μL) 200 μL
PMEL-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Gene Details

Gene Symbol: PMEL

Gene Name: Premelanosome Protein

Chromosome: CHR12: 56347888-56360496

Locus: 12q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ME20-M FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PMEL-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping