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PAK-1 FISH Probe

The PAK-1 FISH probe is designed to hybridize to the PAK-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PKN1-20-OR  (Standard Design) 20 (40 μL) 200 μL
PKN1-20-RE 20 (40 μL) 200 μL
PKN1-20-GO 20 (40 μL) 200 μL
PKN1-20-GR 20 (40 μL) 200 μL
PKN1-20-AQ 20 (40 μL) 200 μL
PKN1-20-DIG 20 (40 μL) 200 μL
PKN1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PKN1

Gene Name: Protein Kinase N1

Chromosome: CHR19: 14544165-14582679

Locus: 19p13.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PAK-1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PKN1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping