PRNP FISH Probe
The PRNP FISH probe is designed to hybridize to the PRNP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRNP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-RE | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-GO | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-GR | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-AQ | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-DIG | 20 (40 μL) | 200 μL |  |
|
| PRNP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: PRNP
Gene Name: Prion Protein
Chromosome: CHR20: 4666796-4682234
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: PRNP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRNP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping