SLC12A1 FISH Probe
The SLC12A1 FISH probe is designed to hybridize to the SLC12A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC12A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-RE | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-GO | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-GR | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SLC12A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: SLC12A1
Gene Name: Solute Carrier Family 12 Member 1
Chromosome: CHR15: 48498497-48596275
Locus: 15q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SLC12A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SLC12A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping