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TGFB FISH Probe

The TGFB FISH probe is designed to hybridize to the TGFB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TGFB1-20-OR  (Standard Design) 20 (40 μL) 200 μL
TGFB1-20-RE 20 (40 μL) 200 μL
TGFB1-20-GO 20 (40 μL) 200 μL
TGFB1-20-GR 20 (40 μL) 200 μL
TGFB1-20-AQ 20 (40 μL) 200 μL
TGFB1-20-DIG 20 (40 μL) 200 μL
TGFB1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]

Gene Details

Gene Symbol: TGFB1

Gene Name: Transforming Growth Factor Beta 1

Chromosome: CHR19: 41836811-41859831

Locus: 19q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TGFB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TGFB1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping