TNFSF8 FISH Probe
The TNFSF8 FISH probe is designed to hybridize to the TNFSF8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNFSF8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-RE | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-GO | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-GR | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-AQ | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-DIG | 20 (40 μL) | 200 μL |  |
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| TNFSF8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Details
Gene Symbol: TNFSF8
Gene Name: TNF Superfamily Member 8
Chromosome: CHR9: 117665123-117692770
Locus: 9q32-q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TNFSF8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFSF8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping