TRIM5 FISH Probe
The TRIM5 FISH probe is designed to hybridize to the TRIM5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIM5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-RE | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-GO | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-GR | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-AQ | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-DIG | 20 (40 μL) | 200 μL |  |
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| TRIM5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
Gene Details
Gene Symbol: TRIM5
Gene Name: Tripartite Motif Containing 5
Chromosome: CHR11: 5684424-5706339
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TRIM5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRIM5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping