REL FISH Probe
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family. c-Rel has an important role in B-cell survival and proliferation. The REL gene is amplified or mutated in several B-cell lymphomas, including diffuse large B-cell lymphoma and Hodgkin lymphoma.
Empire Genomics has developed a REL FISH Probe Set that can be used to detect REL gene rearrangements. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| REL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| REL-20-RE | 20 (40 μL) | 200 μL |
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| REL-20-AQ | 20 (40 μL) | 200 μL |
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| REL-20-GR | 20 (40 μL) | 200 μL |
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| REL-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: REL
Gene Name: REL Proto-oncogene, NF-kB Subunit
Chromosome: CHR2: 61108751-61150178
Locus: 2p16.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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